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Once-weekly semaglutide, a novel GLP-1 analog, received approval for use in the USA in December 2017
Semaglutide Medications and Eye Health Schedule Today Understanding Semaglutide and Your Eyes Semaglutide medications work by improving how your body manages blood sugar, but rapid changes in glucose levels can temporarily affect your vision
Cannabinoid receptor 1 antagonist treatment induces glucagon release and shows an additive therapeutic effect with GLP-1 agonist in diet-induced obese mice
Studies of similar subcutaneous therapies (e.g., insulin) show 4 mm needles are effective for the vast majority of patients, reducing the risk of accidentally injecting into muscle (intramuscular injection)
![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/359199250/figure/fig1/AS:11431281081130351@1661532031197/Physiologic-effects-of-GLP-1-adapted-from-Granata-et-al-11.png)
