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Semaglutide tends to be the better fit when: the goal is a 10 to 15 percent weight reduction, the patient has documented cardiovascular disease or is at high cardiovascular risk and wants the medication with the most outcomes data, cost or access constraints favor it, or the patient has tolerated single-pathway GLP-1s well in the past
However, semaglutide itself does not directly bind or regulate cortisol production in the adrenal glands
Disclaimer: This content is for educational purposes only and does not constitute medical advice
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