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Four multiple comparisons were performed between the vehicle-treated db/db groups and the remaining groups

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A generic drug is approved by FDA under 505(j) of the FD&C Act and meets all of the requirements of that section (including establishing therapeutic equivalence to a brand name drug, among others), while a compounded drug is not approved by FDA

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GLP-1 was first identified in the 1980s, and since then, its significance in regulating metabolism and its therapeutic potential for diabetes and obesity have been extensively studied

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