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Dissociative anesthetics: Ketamine and N 2 O predominantly affect glutamatergic transmission by antagonizing NMDA receptors (NMDARs), causing excitotoxicity, mitochondrial dysfunction, and neuronal apoptosis

While some compounding pharmacies may technically be able to prepare higher doses, the clinical safety data supports the 15 mg ceiling

weight management The primary draw: FDA-approved as Wegovy for chronic weight management and studied extensively for appetite-driven fat loss