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It follows that bilirubin may induce apoptosis in tumor cells by upregulating Bax and downregulating Bcl-2
The increased accumulation of iron in senescent cells was confirmed by MS and using a colourimetric assay (Extended Data Fig
While it does not function as a sunscreen or exfoliant, it supports the skins ability to manage oxidative stress, which is linked to visible ageing and uneven pigmentation
To understand the nature of X(PC)s off-target cleavage activity more deeply, we began by investigating cleavage of downstream caspase-1 substrates and observed that X(PC) likely cleaved IL-1 (Fig
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