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It is currently under clinical investigation for the management of obesity and type 2 diabetes (as demonstrated in a phase 2 trial published in the New England Journal of Medicine), and as of the time of writing, it has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA)

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The Danish company Novo Nordisk sells several different brand names with semaglutide as an active ingredient: notably, Ozempic, for diabetes and reducing cardiovascular event risks, and Wegovy, for weight loss and reducing cardiovascular event risks