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Arthritis Res Ther (2020) 22(1):116

The adjusted difference in mean IWQOL-Lite total score between groups from was 14.3 (95% CI 6.5 to 22.1)

Specifically, people with a personal or family history of thyroid cancer, including medullary thyroid carcinoma (MTC), should not use semaglutide GLP-1 due to an increased risk of developing thyroid tumors