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In one of the longest published studies until today (with a follow-up of 6 years) it was clearly shown that in patients with T2D and NAFLD the severity of both steatosis and fibrosis were strongly and inversely related to the Matsuda Index of insulin sensitivity, emphasizing the crucial role of PIO (currently the most well-studied TZD) that targets IR directly to its genesis [128]
A study published in JAMA Network Open in 2022 found that patients using GLP-1 drugs had 17% lower overall healthcare costs compared to those not using these medications
If you and your doctor find that none of them work for you without causing severe or long-lasting diarrhea, you may decide together to stop treatment and try another type of weight management medication
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