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Hives are raised, red, itchy welts that form when the body releases histamine and other inflammatory mediators into the skin

This is illustrative, not a guarantee individual pacing varies as discussed above

The efficacy regarding lowering glycemia and body weight is stronger than that of GLP-1RAs while the safety profile and the incidence of adverse events seem comparable

In this context, the functional mimicry of GLP-1 should be considered worthwhile if the designed agonist can act as a biased agonist of GLP-1R, selectively triggering anti-inflammatory signaling pathways that can aid in reducing the growth and differentiation of certain types of neuroendocrine tumors