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Critics counter that no published in vivo studies demonstrate tumor inhibition
Consequently, GSTP inhibition effectively induces apoptosis, revealing its role as a key regulatory node in liver cancer (183)
Additionally, in concanavalin A- (Con A)-induced AIH, pretreatment with Fer-1 reduced the severity of Con A-induced liver lesions and the occurrence of ferroptosis events, including the elevation of hepatic GSH, GPX4, and system Xc-expressions and downregulation of ferrous iron levels in liver tissues (Zeng et al., 2020)
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