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Animal studies suggest that it reduces NNMT activity, leading to better NAD+ retention, improved metabolic efficiency, and reduced fat mass
For severe deficiency, the AAFP recommends loading doses typically daily or every other day for one to two weeks followed by monthly maintenance injections
The trade-off is more time off the peptide, but often better results during active cycles
When comparing cyanocobalamin vs methylcobalamin, the best B12 injection depends on individual needs
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