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Most patients begin experiencing initial improvements in sleep and energy within the first month, with significant body composition changes becoming evident after three to six months of consistent therapy under medical supervision

Mitochondrial genome instability promotes mtDNA release that engages cGAS-STING and elevates interferon-stimulated gene expression, strengthening antiviral defense, but prolonged activation provides a route to excessive inflammatory signaling that can contribute to immunopathology during infection (122)

The brain is a delicate organ that can efficiently protect itself from harmful compounds and precisely regulate its microenvironment

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