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(2007) Hepatology 45:1118
Esta idea represent un avance decisivo ya que durante dcadas la naturaleza de las protenas haba sido motivo de intenso debate en la comunidad cientfica
It is evident that CNS GLP-1R signaling is essential for mediating the pharmacological action of GLP-1R agonists on energy metabolism as genetic deletion of CNS GLP-1R signaling in mice ablates the action of peripherally administered liraglutide on food intake and body weight reduction (Sisley et al., 2014)
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