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692,693 Mutations in key TCA cycle enzymes, such as SDH, fumarate hydratase, and IDH, lead to TCA cycle dysfunction and mitochondrial metabolic defects across various human cancers
It also influences insulin regulation, which is crucial for managing body weight and fat storage
Signaling pathway analysis identified 47 pathways, of which the cytokine-cytokine receptor interaction was most significantly associated with G6PD-related genes
These may include headaches, nausea, injection site reactions since its administered via a subcutaneous injection, water retention, and altered cortisol levels
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