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Prolonged Stimulation of Growth Hormone and Insulin-Like Growth Factor I Secretion by CJC-1295 in Healthy Adults Journal of Clinical Endocrinology & Metabolism Single injection of CJC-1295 produced dose-dependent GH increases of 210 fold sustained for 6+ days and IGF-I elevations of 1.53 fold for 911 days, with half-life of 5.88.1 days
The pharmacological mechanisms of GLP-1 agonists operate independently of thyroid function, targeting appetite regulation and glucose metabolism rather than thyroid hormone synthesis or action
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