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Kelch ECH-associating protein 1 (Keap-1) followed a similar trend ( P =0.05) (Figure 5a)
This strategy was based on previous structural data showing that position 5 of the FFAT core motif is located within a hydrophobic pocket in the MSP domain of VAP 41 , with previous studies indicating that introducing a negative charge in this position causes a steric hindrance which effectively disrupts FFAT motifVAP interaction 42
Intravenous (IV) Therapy: Because IV therapy is more potent, the risks are higher
The treatment most patients underestimate
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