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It means the gray market wasn't a failure of patients
Chronic conditions such as psoriasis and hidradenitis suppurativa are driven by systemic inflammatory pathways that overlap with obesity and insulin resistance
If standard doses are not tolerated, clinically appropriate alternatives might include slower titration (still within SmPC guidelines), switching to a different GLP-1 receptor agonist, considering other medication classes, enhancing diet/lifestyle support, or specialist review
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