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Evaluations of its safety and effectiveness have been conducted within the fields of endocrinology, oncology, and neurology [3]
The long-term effects of GLP-1 are not yet fully clear, but documented side effects observed within a year of usage include (in descending order of frequency) digestive system issues, abdominal and pelvic pain, nausea and vomiting, hypertension and dehydration
According to Riccardo Perfetti and colleagues from Cedars-Sinai Medical Center, Division of Endocrinology in Los Angeles, California, continuous infusion of GLP-1 to both young and old rats demonstrated an up-regulation of pancreatic-duodenum homeobox-1 (PDX-1) expression in islets and total pancreas which is essential for pancreogenesis, pancreatic cell differentiation, and maturation
Wilson JM, Lin Y, Luo MJ, Considine G, Cox AL, Bowsman LM, et al
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