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The theoretical difference comes from retatrutide's glucagon activity
Irisin and incretin hormones: similarities, differences, and implications in type 2 diabetes and obesity
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Another study on GLP-1 polymorphisms found that two GLP-1 polymorphisms, A allele in rs10305492 and C allele in rs1042044, show associations with response bias in a probabilistic reward task (PRT), a laboratory-based measurement of anhedonia (Yapici-Eser et al., 2020)
