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They are generally well-tolerated and safe for long-term use
However, these retrospective studies cannot establish causation and may be influenced by unmeasured confounders or selection bias
Current research on the role of the gutbone axis in osteoporosis mainly targets the regulation of bone metabolism by intestinal factors, the pathogenesis and therapeutics of osteoporosis, and the interaction of the gutbone axis with other systems
Limit to 2 cups per day, and if you experience heartburn, switch to lower-acid coffee varieties or reduce intake
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