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An excess of I can increase the antigenicity of Tg, stimulate the production of cytokines and chemokines, which can increase the accumulation of immunocompetent cells in the thyroid gland, increase the level of OS in thyrocytes, stimulate lipid peroxidation and damage to thyroid tissue (43)
The study also shows that women who were diagnosed with both lupus and obesity have more limitations in their daily lives, are more likely to suffer from a disability, and are less likely to be employed than women who are not obese
When tumor cells derived from the LT2MYC model are transfected with locked nucleic acid (LNA) antagonists against miR18a, we observe that GCLC protein expression increases relative to cells treated with control LNA (Fig 3E)
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