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Conclusions At the end of 12 months of follow-up, patients with obesity or overweight with ORCs treated with semaglutide 2.4 mg had a significantly greater reduction in absolute and percentage change in body weight, as well as improvements in cardiometabolic risk factors compared with patients not treated with OM
Specifically, switching from weekly to every-two-weeks dosing maintained approximately 72% of weight loss for semaglutide
And it has not been approved for weight management at its currently available doses
What Does the Evidence Say: A Real-World Comparison Trials comparing Semaglutide vs Tirzepatide One of the most important studies directly compared the two drugs in adults with obesity (but without diabetes)
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