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The study also found that most participants (87.7%) would not have met the eligibility criteria for the head-to-head randomised trial (SUSTAIN-7) that regulators originally used to compare these two drugs

Proc Natl Acad Sci USA 2006;103:51916

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Still, psychiatrists like Georgios Schoretsanitis at the University of Zurich and Chiara Gastaldon at the University of Verona saw a need for additional analyses while the regulatory agencies were reviewing their own datasets