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Godfrey, H., Leibovit-Reiben, Z., et al
This surge in growth hormone elevates circulating insulin-like growth factor 1 (IGF-1), which powers protein synthesis, fat breakdown, and tissue restoration
Hmg-coa reductase inhibitors induce apoptosis of lymphoma cells by promoting ros generation and regulating akt, erk and p38 signals via suppression of mevalonate pathway
These metabolic adaptations during fasting, that are triggered by PPAR, serve to minimize the use of protein and carbohydrates as fuel to allow survival during long periods of energy deprivation
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