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Ann Nutr Metab 2012;60(4):293-297
6.3 Site-specific metabolism: blood cells The observation of a facilitated uptake of 5-(3,4-dihydroxyphenyl)--valerolactone into blood cells and its determination in cell samples of osteoarthritis patients after intake of Pycnogenol (see section 5.2 Distribution into blood cells) prompted systematic advances to elucidate the detailed metabolism of 5-(3,4-dihydroxyphenyl)--valerolactone in human blood cells (28)
It may achieve this through the following pathways: Growth Factor Modulation The peptide has been shown to upregulate the expression of growth hormone receptors (GHR) in tendon fibroblasts
Single-atom catalysts across the periodic table
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