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When used as part of a broader weight management strategy, including diet, exercise, and lifestyle adjustments, these medications have been shown to be safe and effective for extended periods, with mild side effects like nausea typically diminishing over time
Additionally, drugs targeting hunger or satiety signaling have been actively studied and have shown increased adoption by physicians
Who May Benefit A supportive option for qualified individuals
In vivo studies, such as that by Morris et al., used a preclinical model of a high-fat diet in infant rats to mimic insulin resistance, identifying impaired nigrostriatal dopamine function as a consequencea hallmark of PD neuropathology [152]
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