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Nat Commun 17 , 1800 (2026)
The SmPC advises that dose reductions of these medications may be required when starting Ozempic
21) reports +23% at 70 kg and 21% at 120 kg the heavy-end figures disagree between the sponsor paper and the regulator, so treat the low-weight direction as well established and the magnitude at high weight as uncertain
If weight loss plateaus or is less than expected after 3-4 months at the maintenance dose, clinicians should reassess adherence, evaluate for medication interactions, and reinforce lifestyle modifications
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