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Ferroptosis is characterized by increased levels of lipid hydroperoxides and iron overload, and lipoxygenase enzymes could drive ferroptosis via increase production of 5-, 12-, and 15-HpETEs (Dixon et al., 2012
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Moreover, we showed that the downstream fate of cysteine in tumours is not necessarily GSH
2 This level of weight reduction is considered clinically meaningful and surpasses results from similar pharmacotherapies for weight management
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