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Several studies, such as this one, have reported significant pain with water-based injections, and little to no pain with those prepared in saline

Figure 4: Change from Baseline (%) in Body Weight in Study 2 in Patients with Obesity or Overweight and Type 2 Diabetes Note: Displayed results are from the Intent-to-Treat Population

AOD-9604 operates through several metabolic pathways, according to research: It promotes the breakdown of fat and stored triglycerides (lipolysis) into free fatty acids for energy use