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If the insertion tube is lubricated and inserted gently into the rectum, and the coffee is administered at a temperature close to body temperature, there is no reason why there should be any discomfort during the enema
doi: 10.3389/fendo.2021.631463 206 CaiEPIshikawaYZhangWLeiteNCLiJHouSet al
*Correspondence: Aalt Bast, Department of Toxicology, Faculty of Health, Medicine and Life Sciences, Maastricht University, P
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