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A lot is already known about topical depigmenting agents such as hydroquinone, glycolic acid, arbutin, kojic acid, vitamin C, vitamin E and niacinamide, all of which are readily available over-the-counter
Oral GLP-1 therapies can expand the market, but they may not completely overtake injectables
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Both in humans and in rats, IFN- modulates the pigmentation state of melanocytes, but in high concentrations limits melanocytes maturation and differentiation (Natarajan et al., 2014)
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