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Of note, the prevalence of HF varied across these trials from 9% to 24%, and HF events were considered a secondary endpoint
A systematic review and meta-analysis highlighted an increased risk of gallbladder or biliary diseases with the use of GLP-1 receptor agonists, including albiglutide, dulaglutide, exenatide, liraglutide, lixisenatide, and semaglutide [77]
Malabsorption from coeliac disease, Crohns, gastric surgery or long-term metformin and proton-pump inhibitors accounts for much of the rest
Or explain that this type of therapy may have to be part of their weekly treatment plan in order to improve long-term patient outcomes in this patient population
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