Several chemotherapeutic agents, including alkylating agents and platinum-based compounds, are excreted in bodily fluids such as semen, vaginal secretions, saliva, and urine for up to 4872 hours following infusion
Chronic release of proinflammatory cytokines of innate immunity, increased Treg cell activity, aerobic glycolysis of infected cells, and activation of neutrophils by ANCA lead to excessive ROS production, and this could explain the increased oxidative and nitrosative stress, depletion of antioxidant substances, increased aerobic glycolysis in circulating cells, and increased damage to fatty acids, DNA, and proteins that occur in patients with ME/CFS [296,297,298, 360]
Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies
Hong M, Rong J, Tao X, Xu Y