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As an organic solvent, chloroform enabled largescale synthesis of pharmaceuticals, accelerating drug discovery throughout the 20th century
In multiple myeloma (MM), interaction with bone marrow stromal cells (BMSCs) via CD40CD40 ligand (CD40LG) signaling increases iron accumulation and activates the steroid biosynthesis pathway in MM cells, leading to enhanced lanosterol production
PMID: 28392927
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