12,13,14,15,16,17 These tools have illuminated the plasticity of drug-tolerant cells, the immunosuppressive reprogramming of the TME and the dynamic adaptation of cancer ecosystems throughout the course of treatment
Beyond the discussed mechanisms, neurodegeneration may also involve inflammatory responses, energy metabolism defects, endoplasmic reticulum stress, immune dysfunction, and viral infection
J Biol Chem 2004;279:55008-16
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