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Researchers use cagrilintide as a tool compound because it extends amylin-like signaling at receptors in the calcitonin family

Namely, PDH activities were decreased by 33% in hippocampal extracts from the chronic epileptic stage of the pilocarpine mouse model (McDonald et al., 2017), by 43% after a five min flurothyl-elicited seizure (McDonald and Borges, 2017) as well as by 57% during onset of and by 74% 24 h after pilocarpine-induced SE (data unpublished, all p 3.0.CO;2-X J