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Beyond a BMI at or above 27 kg/m2 with weight-related comorbidities or 30 kg/m2 without them, it says providers also assess cardiovascular risk, prior treatment history, metabolic markers, age, medication interactions and contraindications before deciding

In a placebo-controlled trial of overweight women, 1 mg per day of chromium picolinate for 8 weeks reduced daily food intake, hunger levels, and cravings for fats

While this approach avoids nausea, it virtually guarantees micronutrient deficiencies and makes the dietary experience unsustainable long-term

When NO levels are too high (which can cause tissue-damaging oxidative stress), BPC-157 helps bring them down