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This can be associated with the development of neurodegenerative disorders [136]
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The science of neuroendocrinology was advanced conceptually 50 years ago by the independent discoveries of Schally, Leeman and Reichlin, demonstrating that the gut peptides thyrotropin-releasing hormone (TRH) ( The BBB does not impair access of sex steroids to the CNS to the same extent as gut peptides
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