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The cells were analyzed on day 0 (iPSCs), day 7 (iNs_D7), and day 14 (iNs_D14)
This study was approved by the Ethics Committee (Comit d'tica de la Investigaci Clnica CEIC, Germans Trias i Pujol University Hospital, coordinator centre), and was conducted in agreement with the Declaration of Helsinki, Organic Law 15/1999 of 13 December about the protection of personal data, Law 14/2007 of 3 July on Biomedical Research, and Guideline for Good Clinical Practice of 2016
N-acetylcysteine (NAC) is a well-studied glutathione precursor used in NHS hospitals for paracetamol overdose, with doses of 6001,800 mg daily studied in research
Continuous low-dose maintenance works well for chronic conditions without loss of effect
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