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True B12 deficiency can show up as increased shedding, brittle hair, slow regrowth, and pale or inflamed skin especially in vegans, older adults, and people on certain medications
Increases synaptic proteins (synaptophysin, PSD-95) supporting connections between retinal neurons and from retina to brain
Class-based models put exposure per milligram about 10% to 25% above the 240 lb trial mean across this range. Resting heart-rate response may also exceed the trials near-zero average
Enteric oxalate secretion mediated by Slc26a6 defends against hyperoxalemia in murine models of chronic kidney disease
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