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Although the exact mechanism of how coffee enemas cause proctocolitis is not known, it is suspected that the proctocolitis is caused by the chemicals in coffee enemas, as coffee is a complex mixture of chemical compounds that contain more than just caffeine

Reviewed by the PeptideMind Team Updated July 20, 2026 How to Store Peptides: Complete Guide (Fridge, Freezer & Shelf Life) Peptides should be refrigerated at 3646F (28C) as soon as possible

Unfortunately, if you have a deficiency, its likely you also do not produce enough intrinsic factor, or your body has difficulty absorbing it

If anyone here could give me some data on these issues, particularly with references to medical literature, I would greatly appreciate it