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[Glutathione-S-transferase and glutathione in the liver and blood of rats poisoned by [PMID: 7448078] Laboratory literature summary: [Glutathione-S-transferase and glutathione in the liver and blood of rats poisoned by thioacetamide]
Because lasting weight loss starts with understanding why not just how much
Even though lower doses are presumably safer, using them would still require a new pre-IND safety justification, dose-range toxicology studies, and possibly a new manufacturing lot release. That would add ~12 years of delay
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