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The most prevalent adverse events were nausea (15.4%-19.1%), diarrhea (10.1%-12.6%), vomiting (6.6%-7.5%), and constipation (5.8%-6.5%)
On the other hand, many lactobacilli are not capable of producing folate de novo because some genes coding for enzymes involved in folate biosynthesis are lacking in their genome
Similarly, four weeks of chronic unpredictable mild stress in male mice reduces microglial KMO via corticosterone, increasing hippocampal KYNA and producing depressive-like behaviours that are rescued by nicotine-mediated 7nAChR activation [72]
In: Dodda JM, Deshmukh K, Bezuidenhout D, editors
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