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That does not prove anything about Dihexa's subjective effects in healthy users, but it is the relevant clinical context and the reason no validated human timeline exists
(2005) in a randomized double-blind clinical study found that a 0.001% Pal-KTTKS formulation significantly reduced wrinkle depth and volume compared to vehicle control after 8 weeks of application
Leuk Lymphoma 19(3-4):235-41, 1995
Laser applications were measured at 1 J cm2 and 3 J cm2
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