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IGF-1 is an important hormone in the pathway that clears amyloid beta from the central nervous system

The company invested in a new Gene & Cell Therapy Services center (18,000 sq ft in Pittsburgh) specifically to handle the unique supply chain of CAR-T and gene therapies ( [33] )

Dosing guidelines suggest starting at a dose of 1.5 milligrams and gradually increasing to the maintenance dose (the dose found to be most effective in clinical trials) of 25 mg, depending on how the person responds and how strong side effects are