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The full therapeutic effect requires sufficient drug concentration across all relevant tissues simultaneously, which is precisely what the dose escalation schedule is designed to achieve
Peptides are short chains of amino acidslike mini proteins
After 56 weeks of treatment, the average weight loss of the patients was 8.40 7.3 kg, and the most common adverse reactions were mild or moderate nausea and diarrhea
In addition, dysbiosis may also contribute to the development and clinical severity of HS (218)
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