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62 H 98 N 16 O 22 1419.55 g/mol 212 H 350 N 56 O 78 S 4963 g/mol Wolverine Blend Mechanism of Action BPC-157 drives angiogenic and growth-factor signaling, including VEGF/VEGFR2 engagement, FAK-paxillin and Rho-GTPase activation in fibroblast cultures, and nitric-oxide pathway modulation via L-NAME-sensitive, L-arginine-rescuable routes
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This leads to the release and subsequent cytoplasmic translocation of p53, which in turn activates a transcription-independent pro-apoptotic pathway, facilitating the selective clearance of senescent cells (Kong et al., 2025
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