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Ikemoto et al., 1997
Food, especially carbs, can dampen the GH pulse because insulin blunts GH signaling
The trial found that after 5 years, Wegovy significantly reduced the risk of death from heart disease by 15% and reduced the risk of cardiovascular events including nonfatal heart attacks and strokes by 20%, compared to an inactive placebo
173 The findings from this study further support ghrelins ability to mediate insulinostatic actions, and that reduction in plasma ghrelin could either promote T2D pathogenesis or be an adaptive response to stop further reduction in insulin secretion in T2D patients
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