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Presented for research literature review only Massy M et al

These shortages were often due to a variety of factors, including manufacturing problems, quality issues, and unexpected spikes in demand

In early 2026, Roche paid $100 million to secure a non-exclusive patent licence from Structures subsidiary Gasherbrum Bio, covering intellectual property relevant to CT-996, the oral GLP-1 compound Roche acquired through its $2.7 billion buyout of Carmot Therapeutics in late 2023