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Malabsorption and genetic defects in the enzyme 5-methyltetrahydrofolate reductase (5-MTHFR) can result in an impaired ability to activate folic acid

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NSAIDs can have a beneficial effect on acute herx reactions Note: Toxin-binder supplements used to bind up and eliminate bacterial endotoxins are understood now to not be of therapeutic benefit in that there are no bacterial endotoxins to bind